Sirolimus Tablets 1 Mg

Find Sirolimus 1mg Tablet Cost, Uses and Substitutes.

Generic Name: Sirolimus(Rapamycin), Brand Name: Rapamune, Other names: Rapamycin, ABI-009

Sirolimus (Siromus) 1 mg Tablet Cost/Price

Our price is low because we want you to get the medicine you need, whether that medicine is expensive or not. We hope to save you money,and fight your health problems.

Sirolimus 1 mg Tablet Cost is around 35 $ per strip( 6 or 10 tablets in each strip, depend on brand) which is taken once tablet a day. The price may vary depending on the brand and availability. We have multiple brand of Sirolimus medicine with different price. You can make inquiry to us and take it in best price. It doesn't matter where you live around the world.

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Uses of Sirolimus (Siromus) Tablets 1 mg

We, humans, are lucky to have a solid inborn immune system. This system rejects the functioning of a newly transplanted organ in our body. So when we require to transplant any of our organs, we must develop favorable conditions in our body so that the new organ does not get rejected.

So our body's immune system needs to be weakened to prevent the new organs from getting rejected. Sirolimus weakens the body's immune system, which prevents organ rejection. It has been commonly used with other medicines in kidney transplantation.

It is also prescribed without other medicines. In the case of lymphangioleiomyomatosis, a rare lung disorder in women, the Sirolimus tablet is given without any other medication. This disorder is common in women and causes them to suffer from breathing problems.

Warnings before use sirolimus Tablets

  • Sirolimus is dangerous when consumed by allergic patients.
  • For patients with lungs or liver transplants, Sirolimus is like poison.
  • Frequent blood tests are recommended while on Sirolimus because the body produces lots of
    white blood corpuscles, which may lead to cancer.
  • It can cause kidney transplant failure.
  • The weakening of the immune system may result in severe viral fever.
  • You should not consume it during pregnancy.
  • It is better to use strict birth controls if you have consumed Sirolimus. These must be maintained
    up to 12 weeks after taking the final dose of this medicine.
  • Breastfeeding should be canceled while you are using it
  • Sirolimus is for children above 13 years of age.

How to use Sirolimus:

This medicine is used mainly to prevent the rejection of a newly transplanted kidney. Immunosuppressants is the class of this medicine. It is consumed to weaken the body's defense system so that the body does not reject any new organ. In certain lung diseases, Sirolimus plays a crucial role.

How to consume:

You are going to get a level of instructions with the Sirolimus. Please read them carefully before consuming them. You must also strictly follow the directions of your doctor.

You must take it by your mouth and swallow at once without crushing, chewing, or grinding. It is enough to take one Sirolimus tablet a day. In case of nausea or sour stomach, take Sirolimus with any food. The medicine dosage will depend on your body weight, the medication you are consuming daily, medical conditions, medical tests, and the way your body responds.

Sirolimus once a day is enough. If you are also consuming cyclosporine, you must remember to take it, in the same way every time. This tablet is to be swallowed as a whole without being chewed, crushed, or broken. You must read the instructions carefully before consuming. You must ask your doctor or pharmacist for help if you do not understand the instructions.

You must take this medicine daily to extract the maximum output of it. Fix a time and take medication at the same time daily. Sirolimus is something serious, and you must not dare to take it in more dosage than prescribed. It is a misconception that consuming an increased dose will give more results. Instead, the adverse side effects may increase and gradually exploit your body.

Sirolimus is available in oral liquid form also. You must take it with either water or orange juice. No other liquids must accompany your consumption of Sirolimus. Measure the liquids carefully using the dosing syringe.

Your body will be more prone to infections after you start taking doses of Sirolimus. Thus frequent medical tests are necessary to stay aware of the condition of your body. The consumption of the following dosages of Sirolimus can be delayed if found necessary.

If you have started using Sirolimus, you should not stop it without consulting a doctor; otherwise, your body may be in more trouble. It would be better if stored at room temperature. Ensure that Sirolimus tablets are away from heat, moisture, and sunlight.

If you have Sirolimus in liquid form, try to store it in the refrigerator. Make sure that it should not freeze inside. After keeping it in the refrigerator, you might notice the liquid slightly hazed. But it disappears no sonner it is brought to room temperature.

Sirolimus Side effects

Before consuming Sirolimus tablets, you must be well informed that this medicine is severe. It can damage the brain temporarily through brain infections. Permanent damages may also be incurred that can extend even up to the death of the individual. It is advised to consult a doctor even in case of a slight change in mental condition, vision, natural thinking, hearing, or speech.

Consult doctors if you find allergic symptoms, including rash, hives, or peeling skin; wheezing, swelling of the tongue, throat, face, difficulty breathing, chest pain, or tightness. If your skin gets wounded, it is healing slow or oozing out, and you must visit a doctor.

A new mole on your skin or lesion can also be harmful. Normal bleeding is also among the common side effect. If your chest starts paining suddenly or you feel uncomfortable breathing, you are requested to take it seriously.

It can also increase your cholesterol level. So it would be better if you kept your cholesterol levels in check while consuming this. That means you have to focus on your diet and simultaneously take medications to prevent the accumulation of cholesterol.

Many people suffer from tiredness around the regions of their transplanted kidneys. Low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet are also important issues to consider.

It would help if you did not panic while consuming Sirolimus as your doctor has judged it necessary and safe for you to take it. The side effects are not found in everybody. These are the only possible effects that can be seen.


Before your doctor or pharmacist prescribe you Sirolimus, unfold all the history about your body to your pharmacist. If you have surgery on the liver, lungs, kidney, heart, etc., you must let him know about it. When you are in Sirolimus, try to keep your body clean and germ-free every time, as in this period, your body will be more prone to infections.

Wash your hands frequently and keep a safe distance from the crowd. You must avoid coming in contact with persons suffering from severe immediately. If you have, by chance, come in contact with infected people, consult your doctor immediately.

If you go through any surgery, tell the doctor recommending your surgery about your daily consumption of Sirolimus and other daily medications you are going through.

Also, breastfeeding is better to be avoided during the period of sirolimus dosage. This is because the medication can pass through the breast milk to the nourishing child and develop in him and weak immune system. Consult your doctor if you necessarily have to breastfeed.

SirolimusInteraction with another Medicine

Interaction of Sirolimus with other drugs main result to many other negative impacts on your body. You must consult the doctor before taking any extra medicine while on a daily dosage of Sirolimus.

ACE inhibitors such as benazepril lisinopril interact with Sirolimus and weaken the body more. Other drugs such as natalizumab, rituximab, tacrolimus react more violently with Sirolimus and degrade the body more.

Azole antifungals such as , erythromycin, mifepristone,itraconazole, ketoconazole, voriconazole, enzalutamide, macrolide antibiotics such as clarithromycin HIV and HCV protease inhibitors such as ritonavir, telaprevir, indinavir, rifamycins such as rifampin, rifabutin does the task of removing Sirolimus from the body. This cuts the productivity of the medicine.

Sirolimus tablets should not be flushed through toilets or poured in drains unless advised. You must consult a pharmacist or the local disposal center before disposing of Sirolimus.

Buy Sirolimus(Rapamycin) Tablests Substitutes by Polpular Brand


Rapacan(Sirolimus) 1 mg tablets

It has been commonly used with other medicines in kidney transplantation


Siromus (Sirolimus) 1 mg tablets

It has been commonly used with other medicines in kidney transplantation



Some FAQs about Sirolimus Tablets

1. What is sirolimus?

Sirolimus is used to prevent organ rejection in transplant patients. It regulates the body's immune response to allow the body to accept the new organ. Rejection usually occurs because of an attack on the transplant recipient's own immune system, even in people who receive kidney transplants.

2. What is the drug sirolimus used for?

Sirolimus is a selective immunosuppressant used to stop organ rejection after transplantation. Sirolimus is used with other medications to lower your immune system so your body can accept the new organ. This drug can also treat lymphangioleiomyomatosis lung disease when used alone.

3. What type of drug is sirolimus?

Sirolimus is used with other medications to prevent the body from rejecting a kidney transplant. It belongs to a group of drugs known as immunosuppressants that help to lower the body's immune response. When a patient receives an organ transplant, the body's white blood cells try to remove (reject) the transplanted organ.

4. What are side effects of taking sirolimus?

Most side effects do not require medical attention and will go away as your body adjusts to the medication. Call your doctor if they persist or if you are concerned about them

Common side effects of Sirolimus

  • nauseous
  • Increased levels of lipids in the blood
  • Low platelets
  • headache
  • stomach ache
  • Fever
  • anemia (low red blood cell count)
  • Urinary tract infection
  • Diarrhea
  • High blood pressure
  • Increased levels of creatinine in the blood
  • joint pain
  • edema (swelling)
5. What is the mechanism of action of sirolimus?

Sirolimus is a drug used to treat cancer and kidney disease. It works by stopping white blood cells from growing and multiplying, therefore preventing the immune system from attacking healthy tissue. In addition, Sirolimus reduces the production of antibodies, which are proteins made by the immune system to fight infection.

6. Does sirolimus cause memory loss?

Seek medical attention immediately if you notice any of these side effects: clumsiness, loss of coordination/balance, weakness, sudden changes in thinking (such as confusion, difficulty concentrating, memory loss), difficulty speaking/walking, seizures, blurred vision. Sirolimus may slow the healing of wounds after surgery.

7. Is sirolimus a chemotherapy?

Sirolimus is a Chemotherapy drug such as sirolimus that uses different ways to stop tumor cells from dividing so they stop growing or die. Chemotherapy can shrink tumors so that they can be removed if given before surgery.

8. Does sirolimus cause liver damage?

The liver injury caused by sirolimus therapy is usually mild and transient, and it will resolve on its own or with dose modification or discontinuation. There is no evidence that sirolimus causes acute liver failure or vanishing bile duct syndrome.

9. Do sirolimus side effects go away?

Sirolimus can cause some side effects, but most of them don't need medical attention. These side effects might go away as your body gets used to the medicine. Your healthcare professional may be able to tell you about ways to prevent or reduce some of the side effects of taking this medication.

10. How fast does sirolimus work?

Upon reintroduction of sirolimus, both patients experienced a significant reduction in bleeding within 48 hours. Infections and oozing also improved in all patients who frequently experienced them prior to treatment. The median frequency of infections per 6 months decreased from 3 to 1, showing a significant improvement in the condition of these patients.

11. Does sirolimus cause high blood pressure?

Some things to keep in mind while taking Rapamune (sirolimus): always tell your healthcare providers that you are taking this medication, including doctors, nurses, pharmacists, and dentists. High blood pressure is a common side effect of Rapamune, so be sure to monitor your blood pressure levels closely.

12. Is sirolimus toxic?

The most common side effects of sirolimus treatment are a decrease in blood platelets and an increase in cholesterol levels. Additionally, patients receiving sirolimus and cyclosporine have been shown to have higher levels of creatinine in their blood compared to those taking cyclosporine and azathioprine, raising some concern.

13. When should sirolimus levels be checked?

Sirolimus levels are typically monitored every five days through a blood test. To perform the test, a healthcare provider will draw 5 mL of blood from a vein in your arm and send it to a laboratory for analysis. The results of the test can help guide sirolimus dosing to ensure therapeutic effectiveness and minimize side effects.

14. Does rapamycin cause weight gain?

Although rapamycin has been approved as a pharmaceutical to prevent organ rejection, there are numerous side effects. The biggest problem is that it can cause insulin resistance in patients who take the drug for extended periods of time. There is also an increase in blood sugar levels and weight gain, thus leading to obesity in some cases. 

15. How long does sirolimus stay in your system?

Sirolimus is an immunosuppressant often used in the prevention of kidney transplant rejection. Sirolimus is broken down in the liver and its elimination half-life is 57-63 hours. This drug is metabolized in the liver and the bile, which allows you to expel most of it via feces.

16. Is sirolimus an immunosuppressant drug?

Sirolimus will become the new standard for immunosuppressant drugs, being released for use on transplant patients and eventually for all transplant patients in the future.

17. Where is sirolimus absorbed?

Sirolimus is an immunosuppressant drug that treats cancer and other autoimmune diseases. It goes through a metabolic process to be converted into its active form before it enters the bloodstream, but some of it may be removed from the body by sentinel cells in the liver called Kupffer's Cells.

18. How much does Rapamune cost?

Rapamune oral tablet 0.5 mg costs around $1,750 for a supply of 100 tablets, depending on the pharmacy you visit. Prices are valid only for cash paying customers and do not apply to insurance plans. When considering the overall value offered by Rapamune oral tablet 0.5 mg, however, patient costs seem even more reasonable.

19. What is the brand name of sirolimus?

Sirolimus is a biopharmaceutical immunosuppressant drug that was initially studied for use in transplant recipients, and is now also sold for general use. It has had many different brand names, including Rapamune, but its name in generic form is everolimus. Sirolimus prevents the body from rejecting transplanted organs and other types of tissue transplants by preventing certain cells of the immune system from functioning normally.

20. Is sirolimus better than tacrolimus?

So, our meta-analysis of randomized trials and cost evaluation model show that renal transplant recipients who are maintained on tacrolimus have better outcomes than those maintained on sirolimus. And tacrolimus may be more cost-effective than sirolimus for the primary prevention of AR in renal transplant.

21. What are the side effects of rapamycin?

Patients could experience ringing in their ears, confusion, hallucinations, seizures, severe nausea and vomiting, bloody stools or coughing up blood. The manufacturer says that fever and swelling are also possible side effects. The manufacturer recommends that you do not use the product if you are pregnant, breastfeeding or on prescription medications.

22. How is sirolimus metabolized?

Sirolimus is metabolized extensively by the gastrointestinal system and the liver. More than 70% of the drug is processed in the intestines, while at least 10% more is processed in the liver. Through this processing, three major active metabolites are formed: two hydroxylated derivatives and one demethylated derivative.

23. Does sirolimus cause diarrhea?

Sirolimus is a powerful macrolide that is widely used by transplant clinics. The most common side effects of sirolimus are high levels of triglycerides, cholesterol, and blood pressure; as well as a rash, and some well-tolerated diarrhea.

24. Is sirolimus safe to use?

Sirolimus was proven effective and safe in the treatment of vascular anomalies, which are a spectrum of rare diseases classified into vascular tumors and malformations. The International Society for the Study of Vascular Anomalies (ISSVA) has adopted a new classification system for vascular anomalies. This system is based on the most recent scientific evidence and advances in the field, and will help doctors better understand and treat these conditions.

25. When was sirolimus approved?

The Food and Drug Administration (FDA) approved sirolimus protein-bound particles for injectable suspension (albumin-bound) (Fyarro, Aadi Bioscience, Inc.) on November 22, 2021, for adult patients with locally advanced unresectable or metastatic malignant perivascular epithelioid cell tumor (PEComa). This is the first FDA-approved treatment for patients with this type of cancer.

26. Does sirolimus cause hair loss?

Sirolimus is a powerful macrolide that is widely used by transplant clinics. There are a lot of different kinds of drugs that act as mTOR inhibitors. Most of them have pretty limited effects on hair loss. In fact, mTOR inhibitors are considered an uncommon cause of hair loss.

27. Does sirolimus cause liver damage?

The liver injury associated with sirolimus therapy is usually mild and transient, typically resolving on its own or with dose modification or discontinuation. In rare cases, more serious liver injury can occur.. Sirolimus has not been linked to any cases of acute liver failure or vanishing bile duct syndrome.

28. What drug company makes sirolimus?

Pfizer's RAPAMUNE® (sirolimus) has become the first FDA-approved treatment for lymphangioleiomyomatosis (LAM), a rare progressive lung disease. This is a significant breakthrough for patients suffering from this debilitating and often fatal disease. Pfizer is committed to working with the LAM community to ensure that patients have access to this important new treatment option.

29. Does sirolimus cause constipation?

The most common side effects associated with this drug are peripheral edema, hypertriglyceridemia, hypertension, hypercholesterolemia, increased creatinine, constipation, abdominal pain, diarrhea, headache, fever, urinary tract infection, anemia, nausea, arthralgia, pain, and thrombocytopenia.

30. Does sirolimus cause low platelets?

In Addition to preventing rejection of solid organ transplants, sirolimus-eluting stents are being studied as a potential treatment for coronary artery restenosis.  Thrombocytopenia is a known side effect of sirolimus that limits its use.

31. What age can you start rapamycin?

Although rapamycin has been shown to be effective in delaying the aging process, it is unclear whether earlier treatment is more effective than starting at a later age. Harrison et al. (2009) suggests that starting rapamycin delivery at 600 days of age is nearly as effective as 9 months, while Miller et al. (2011). Additionally, there is growing evidence that several measures of health span can be positively impacted from rapamycin treatment.

32. Can rapamycin cause depression?

Rapamycin (also called Sirolimus) is known to have an impact on depressive symptoms based on some preclinical or animal studies. Some patients who take sirolimus may experience an improvement in their depressive symptoms. However, more research is still needed in order to confirm this impact.

33. Can sirolimus cause blood clots?

Out of 100 people who take Sirolimus, between 4 and 20 may experience one or more of the following side effects: a blood clot that could lead to confusion, swelling, pain, or shortness of breath; or an allergic reaction that might cause a rash, low blood pressure, wheezing, swelling of the face or throat.

34. Should sirolimus be taken with food?

Sirolimus should be taken at the same time each day, with or without food. Taking sirolimus consistently helps to maintain consistent blood levels of the drug. Consistent intake is important to ensure that the drug reaches its full potential to treat your condition.

35. How expensive is sirolimus?

Sirolimus is a generic prescription drug that, in combination with cyclosporine and steroids, works to suppress the immune system to prevent organ rejection after kidney transplantation in patients 13 and older. The retail price for Sirolimus is $503.72 for 30, 1MG Tablet, but it can be reduced to $70.91 for 30, 1mg Tablet.

36. How much does Rapamune cost?

Rapamune is a medication used to prevent organ transplant rejection. It is available in oral tablet form, with a 0.5 mg dose costing around $1,750 for 100 tablets. Prices will vary depending on the pharmacy you visit, and cash paying customers typically receive the best rates.

37. Is there a generic for sirolimus?

The Food and Drug Administration (FDA) has approved generic sirolimus tablets for the prophylaxis of organ rejection. Sirolimus is an mTOR inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in patients receiving solid organ transplants.

38. Is sirolimus the same as Rapamune?

Sirolimus is same as Rapamune and also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumor (PEComa). Rapamune, the brand name for sirolimus, is a medication that is approved by the FDA for the treatment of several conditions, including those mentioned above.

39. What is the brand name of sirolimus?

Sirolimus systemic is a selective immunosuppressant used in the treatment of lymphangioleiomyomatosis and organ transplant rejection. This medicine belongs to a group of medicines known as immunosuppressive agents. It is available only with your doctor's prescription.

40. How much does rapamycin cost?

The average cost for a Rapamycin oral tablet 0.5 mg is $1,750 for a supply of 100 tablets. However, the price you pay for this medication will depend on the specific pharmacy you visit. Keep in mind that prices listed here are only for cash-paying customers and may not be valid if you have insurance coverage.

41. What does rapamycin do?

Rapamycin is a powerful antibiotic. Rapamycin is a macrolide that has potent antitumor and immunosuppressive activity. Rapamycin is used in clinical settings to prevent rejection in organ transplantation and to treat certain types of cancer.

42. Where to buy Rapamycin?

Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. You can buy Sirolimus online through SirolimusIndia. SirolimusIndia is a leading provider of generic medicines.


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